Derms Say Vitamin C Is the Ultimate Brightening, Anti-Aging Antioxidant—Here's Why

vitamin c

Liz DeSousa for Byrdie

While some skincare ingredients are shrouded in obscurity, others are much more familiar—one of the latter being vitamin C. It's so ubiquitous in brightening products, wrinkle-reducing eye creams, anti-aging serums, and other treatments that whether you're just dabbling in skincare or you're the friend everyone texts for advice, we're willing to bet you've heard of the powerful antioxidant. But if you have yet to incorporate a vitamin C product into your skin routine, allow us to convince you of the many reasons why you should. Ahead, experts share all the need-to-know details about vitamin C, including its benefits and the most effective ways to use it.

Keep reading for the complete guide to the popular antioxidant ingredient.

Vitamin C

Type of ingredient: Antioxidant

Main benefits: Protects against free radical damage, evens skin tone, and promotes collagen production.

Who should use it: Vitamin C is not recommended for those with extremely sensitive skin and can be problematic for those with oily skin. Herrmann recommends asking your board-certified dermatologist which brand may be best suited for your skin type. 

How often can you use it: Herrmann recommends using vitamin C daily or every other day.

Works well with: Vitamin C works well with complementing antioxidants like vitamin E and ferulic acid, which will boost the efficacy and stability of the molecule.

Don't use with: Avoid using with benzoyl peroxide, which can oxidize the vitamin C and make it useless very quickly. Also avoid using vitamin C with other acids, which may cause excessive skin irritation, especially if used daily. And lastly, don't use with retinol, which can make the vitamin C more unstable and less likely to penetrate the skin.

What Is Vitamin C?

According to cosmetic chemist and founder of BeautyStat Cosmetics Ron Robinson, vitamin C is an essential nutrient required for the growth and repair of tissues in all parts of the body, including the skin, but we cannot produce it on our own. The powerful antioxidant is found naturally in fruits and vegetables and commonly produced synthetically in skincare products, such as moisturizers, toners, and, most often, serums.

"It is important to note that vitamin C has both active and inactive forms," explains Anna Guanche, MD, a board-certified dermatologist, celebrity beauty expert, and founder of Bella Skin Institute in Calabasas, CA. "Depending on the skincare formulation, applying vitamin C can do absolutely nothing or can work as a powerful antioxidant." The first form of vitamin C worth mentioning is the pure form, L-ascorbic acid. Jennifer Herrmann, MD, board-certified dermatologist who practices in Beverly Hills, CA, says this is the most biologically active and well-studied form of vitamin C, but there are also several vitamin C derivatives, such as sodium ascorbyl phosphate, ascorbyl palmitate, retinyl ascorbate, tetrahexyldecyl ascorbate, and magnesium ascorbyl phosphate. "These derivatives are not pure vitamin C, rather they are combined with other ingredients, which might help to keep the vitamin C stable," Robinson adds. "So when these derivatives come in contact with the skin, they release the pure vitamin C onto the skin." For example, he says if a product contains 10 percent of one of these derivatives, it might only release 3 percent of pure vitamin C on the skin. Herrmann adds that the variants mostly differ in their hydrophilicity (their ability to easily dissolve in water) and pH.

How Does It Work?

To understand how vitamin C works, we first need to know how free radicals damage the skin. There are three types of free radicals, but Renée Rouleau, celebrity esthetician and founder of her eponymous skincare brand is mainly concerned with the reactive oxygen species (ROS). "We are exposed to ROS from the air we breathe (oxygen), cigarette smoke, UV sunlight, stress, and smog," she says. The effects of ROS are no joke: They damage the dermis of the skin and alter DNA, the moisture barrier, skin texture, color, and cell functioning.

To demonstrate the effects of ROS and oxidative stress to the naked eye—and to prove how vitamin C works to combat them—Rouleau devised a simple experiment involving an apple. She coated one end of a slice with a thin layer of vitamin C serum and left the other side completely untouched. Then, she waited for three hours. Here's what happened:

Apple vitamin C experiment
 Renée Rouleau

As you can see, the side of the apple that was coated with the vitamin C serum didn't oxidize at all. "This shows how topical vitamin C can prevent oxidation, and therefore, slow down the visible appearance of aging," Rouleau says.

Vitamin C is very reactive and easily loses its antioxidant properties when exposed to heat, light, air, and other chemicals. To prevent it from oxidizing and deactivating, use vitamin C products that come in air-tight, opaque packages and store them in a cool, dark environment. If your product has turned brown, Herrmann says it’s best to toss it and replace it with a new bottle, as this change in color indicates that the formula has oxidized and is no longer effective.

Benefits of Vitamin C for Skin

Vitamin C is an impressive skincare ingredient that is shown to be effective in the following areas:

  • Protects against environmental stressors: As an antioxidant, one of vitamin C’s main functions is protecting the skin. "Normal cellular processes, as well as environmental insults like ultraviolet light and pollution, create free radicals in the skin," Herrmann explains. "Free radicals are inherently unstable molecules that damage cells, promoting skin dullness, wrinkles, and even cancers." Guanche adds, "Vitamin C is an antioxidant, which means that it can protect skin from damaging free radicals caused by UV exposure." By scavenging these free radicals, vitamin C protects the skin, keeping it healthy and improving visible signs of aging.
  • Promotes collagen production: Vitamin C also plays an important role in collagen synthesis. "Collagen gives our skin support and structure, and as it degrades with age, we begin to notice wrinkles and lines," Herrmann explains. "Vitamin C is a necessary cofactor for building collagen bundles, without which this process halts."
  • Lightens dark spots: Vitamin C is also helpful in lightening unwanted dark spots and post-inflammatory hyperpigmentation, or decreasing brown discoloration by blocking the pathway of pigment synthesis, according to both Herrmann and Guanche.
woman's vitamin c serum before and after photo

Jenna Ignieri / Design by Cristina Cianci

Vitamin C won't always make a visible difference, but it can make skin brighter and more light-reflective.

Side Effects of Vitamin C

Generally, vitamin C is safe for daily use. However, in high concentrations, it can be irritating, especially if mixed with other acids. Herrmann says those with extremely sensitive skin may not be able to tolerate it, and in which case, should avoid it. Many vitamin C products are also oily, which can be problematic for those with oily skin, so Herrmann recommends consulting your board-certified dermatologist to find a brand or product that is best suited for your skin type. 

How to Use It

One highly debated topic when it comes to vitamin C is what time of the day is best for application. While some argue that morning is best for protecting the skin, others are in favor of nighttime when the skin's vitamin C is most depleted. According to Herrmann, consistency is most important, whether you decide to apply it in the morning or before bed, but avoid using it at the same time as benzoyl peroxide. She also suggests using it daily or every other day, and if you're using a serum (the most common vehicle for vitamin C), apply it after cleansing.

Formulation Considerations

As great as it is, vitamin C isn't without obstacles. First of all, it's inherently unstable and reactive and easily loses its antioxidant properties when exposed to heat, light, and air. As a fix, cosmetic companies have been jumping on the powder form of vitamin C to help improve stability, which would, in theory, make it last longer and increase the shelf life.

Unfortunately, though, Herrmann says it’s not as simple as just mixing one part C-powder to one part of your favorite moisturizer; Vitamin C also does not easily penetrate the skin's barrier. "Depending on the skincare formulation, applying vitamin C can do absolutely nothing or can work as a powerful antioxidant," adds Guanche.

To be effective, Herrmann says vitamin C must be in a concentration of at least 10 percent, and the pH of whatever you’re adding it to must be acidic to allow for its absorption. "It’s hard to know the pH of products, and even if you get it right, the powder can crystallize on the skin before it has a chance to absorb, which is a must-do for efficacy." For this reason, Herrmann advises against the DIY trend. "I think it’s wiser to stick with high-quality products that have resulted from extensive research and development to make sure their vitamin C is made available in an optimal formulation for enhanced stability and skin penetration," Herrmann says.

Herrmann also recommends seeking well-researched forms of vitamin C—like L-ascorbic acid—and to opt for formulas that also contain vitamin E, which helps to stabilize vitamin C.

Article Sources
Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.
  1. Telang PS. Vitamin C in dermatology. Indian Dermatol Online J. 2013 Apr;4(2):143-6. doi: 10.4103/2229-5178.110593

  2. Lintner K, Gerstein F, Solish N. A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos® analysis and frequently repeated auto-perception. J Cosmet Dermatol. 2020 Dec;19(12):3262-3269. doi: 10.1111/jocd.13770

  3. Pullar JM, Carr AC, Vissers MCM. The roles of vitamin C in skin healthNutrients. 2017;9(8):866. doi:10.3390/nu9080866

  4. Poljšak B, Dahmane R. Free radicals and extrinsic skin agingDermatol Res Pract. 2012;2012:135206. doi:10.1155/2012/135206

  5. Oregon State University Linus Pauling Institute. Vitamin C and skin health. Updated September, 2011.

  6. Al-Niaimi F, Chiang NYZ. Topical vitamin C and the skin: mechanisms of action and clinical applicationsJ Clin Aesthet Dermatol. 2017;10(7):14-17.

Related Stories