Is Medical-Grade Skincare Really More Potent? A Dermatologist Tells All

You've heard about the magic skin tone–evening powers of SkinCeuticals CE Ferulic and the celebrity outpour of love for brand iS Clinical, both of which are professional-strength and medical-grade. But if you went into a Sephora, Ulta, or Target to pick them up yourself, you'd come out empty-handed. They're primarily sold at medi spas, dermatology offices, or authorized sites like Dermstore, and unfortunately for our bank accounts, they're often quite pricey. But given the loyal following of medical-grade brands and their sworn results, it made us wonder if they're really worth the steep price tag.

"Most of the medical-grade companies will use highly stabilized ingredients that last longer and take longer to degrade," says Rachel Nazarian, MD, of Schweiger Dermatology Group. "Many of them also use more involved mechanisms of absorption to enhance delivery to deeper areas of skin. This is not true for all the medical-grade companies, but certainly for many of them." Some mainstream brands may tout their retinol serum or night cream as an incredible skin-transforming product, but oftentimes there are trace amounts of actives surrounded by synthetic additives, a false claim medical-grade brands don't stand behind.

We get that asking a dermatologist if she supports medical-grade skincare is like asking a pharmacist if they trust prescription pills, but Nazarian says the reason she uses these brands herself over non-medical skincare is because of the strong clinical evidence. "Many of my patients spend hundreds of dollars at Sephora, buying absolute junk," says Nazarian. "I do think that you can find quality ingredients at skincare stores such as Sephora, but they are rare, and you need to know what to look for. Ultimately, I found that the prices of products in general skincare stores are just as expensive as what you can get at the dermatologist office; I recommend even if you want to buy something at Sephora you ask your dermatologist's opinion beforehand to manage expectations on what the product can do. The reason I generally only use the exclusive medical companies is that they have invested in clinical research to guarantee that their products work, generally have more stabilized ingredients, and can prove that they offer results."

Another reason to trust a dermatologist's presumably biased take on professional-strength skincare? Their medical training allows them to ensure that each product is high-quality, capable of guaranteeing results, and is safe for use before offering them to their patient, Nazarian explains. "Whenever we suggest a product for patients, there's an understanding that that product will reflect on us, and it needs to meet our high expectations."

Ready to make the swap for medical-grade products? Take a look at some of our favorite products below.

Still on the hunt for more affordable, professionally vetted skincare options? Take a look at what dermatologists would buy at the drugstore.