The 17 Best Wrinkle Creams of 2022

Our best overall pick is Drunk Elephant’s A-Passioni Retinol Cream

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Best Wrinkle Creams

Byrdie / Chloe Jeong

Texture changes, dark spots, crepey skin, and moisture loss are ordinary effects of aging. We're all for embracing getting older, but the fact is there's still a substantial market for anti-aging products, namely, wrinkle creams. So in the spirit of supporting all types of skincare journeys, we're here to help you find the best ones.

Byrdie Researched & Approved

Because it packs a potent punch with retinol and peptides, Drunk Elephant’s A-Passioni Retinol Cream tops our list of wrinkle creams. If you’re looking for a less pricey product, we recommend RoC Retinol Correxion Deep Wrinkle Night Cream for its resurfacing results.

According to dermatologist Diane Madfes, MD, wrinkles are a result of sun damage, sagging skin, and loss of elasticity. As such, the most effective products for treating them will directly address the causes. Deep wrinkles—those furrows most often noticed around your eyes, mouth, and on your forehead—are more stubborn, but they can be treated, too.

"Look for ingredients that are going to stimulate collagen and elastin, like retinoids, glycolic acids, and peptides," says Madfes. "Remember to protect from future sun damage with UV blockers and DNA repair enzymes."

Scroll down for the best wrinkle creams available today.

Best Overall: Drunk Elephant A-Passioni Retinol Cream

4.5
Drunk Elephant A-Passioni Retinol Cream

Ulta

What We Like
  • Noticeable results

  • Calms inflammation

  • Air-tight pump

  • Fragrance-free

What We Don't Like
  • Expensive

  • Small amount

What do buyers say? 1,200+ Sephora reviewers rated this product 4.2 stars or above.

If we could only pick one wrinkle cream to use until the end of time, we'd go with Drunk Elephant's A-Passioni. It checks two of Madfes's recommended boxes (retinol and peptides) to support collagen production, boost elasticity, firm sagging skin, and—more to the point—reduce the appearance of wrinkles.

What's more, this all-star cream contains ceramides and nourishing fatty acids from plant oils to minimize irritation from the retinol and replenish the skin barrier. It also promises to deliver a plumping effect and an all-around supple, healthy-looking complexion.

A-Passioni is undoubtedly expensive. Nonetheless, we stand behind it not only as one of the best Drunk Elephant products but arguably the best wrinkle cream out there today.

Price at time of publish: $28

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night.

Active Ingredients: Retinol, peptides, plant oils, ceramides, niacinamide | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best Budget: RoC Retinol Correxion Deep Wrinkle Night Cream

4
RoC Retinol Correxion Deep Wrinkle Night Cream

Amazon

What We Like
  • Affordable

  • Resurfacing

  • Noticeable results

What We Don't Like
  • Small amount

On a budget? You can still get great results from an affordable formula. Case in point: RoC. Containing two of Madfes's recommended actives (retinol and glycolic acid) this night cream resurfaces dull, dry skin while smoothing fine lines and supporting collagen production.

Price at time of publish: $30

When to apply: Apply to clean, dry skin (face and neck, if you like) at night.

Active Ingredients: Retinol, squalane, glycolic acid, vitamin C | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: No

RoC Retinol Correxion Deep Wrinkle Night Cream

Byrdie / Leigh Weingus

What Our Testers Say

"Overall, I was very happy with RoC's Retinol Correxion Deep Wrinkle Night Cream. On top of being affordable, it didn't irritate my skin, and I noticed a reduction in fine lines within a week." — Leigh Weingus, Product Tester

Best Drugstore: Neutrogena Rapid Wrinkle Repair Regenerating Anti-Wrinkle Retinol Cream + Hyaluronic Acid

Neutrogena Rapid Wrinkle Repair Regenerating Anti-Wrinkle Retinol Cream + Hyaluronic Acid

Ulta

What We Like
  • Affordable

  • Hydrating

  • Plumping

What We Don't Like
  • Contains synthetic fragrance

When it comes to over-the-counter retinol products, Neutrogena is a drugstore standby. The brand's Regenerating Cream (which can be used daily) combines the vitamin A derivative with hyaluronic acid and glycerin to deliver plumping hydration while smoothing wrinkles.

Price at time of publish: $26

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to sunscreen and makeup.

Active Ingredients: Retinol, hyaluronic acid, glycerin | Skin Type: All | Size: 1.7 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: No

Best With Peptides: Olay Regenerist Micro-Sculpting Cream

3.8
olay-regenerist-micro-sculpting-cream-face-moisturizer-with-niacinamide

Amazon

What We Like
  • Affordable

  • Supports collagen production

  • Improves elasticity

What We Don't Like
  • Contains synthetic fragrance

Madfes recommends wrinkle creams with peptides as they help strengthen the skin while improving firmness and delivering a lifted look. To take it a step further, Olay blends amino acids with niacinamide (vitamin B3) to boost collagen production and radiance on photoaged skin. Use it at night to wake up to the best results.

Price at time of publish: $26

When to apply: Apply a pea-sized amount to clean, dry skin, at night.

Active Ingredients: Peptide complex, amino acids, niacinamide | Skin Type: Mature | Size: 1.7 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: No

What Our Testers Say

"Each morning, I woke up with hydrated skin, and no retinol-induced flakey patches." — Bianca Lambert, Product Tester

Best Daytime: CeraVe Skin Renewing Day Cream with Sunscreen

CeraVe Skin Renewing Day Cream with Sunscreen

Amazon

What We Like
  • Affordable

  • Replenishes skin barrier

  • Air-tight pump

What We Don't Like
  • Reviewers note it's hard to blend

Some would argue the best wrinkle cream is sunscreen, as it helps prevent lines from appearing in the first place. That's why we love CeraVe's Renewing Day Cream, which contains a gentle dose of line-correcting retinol, SPF 30 protection from the sun's damaging rays, and barrier-replenishing ceramides to boot. Use it prior to makeup to allow the product to sink into your skin.

Price at time of publish: $26

When to apply: Apply to clean, dry skin, in the morning (and feel free to layer another SPF on top before applying makeup to ensure you get the most potent sun protection).

Active Ingredients: Octinoxate, zinc oxide, encapsulated retinol, hyaluronic acid, ceramides | Skin Type: Oily, combination, sensitive, mature, balanced | Size: 1.8 oz | SPF: 30 | Byrdie Clean: No | Cruelty-Free: No

Best Overnight: Specific Beauty Radiance Repair Night Treatment

Radiance Repair Night Treatment
What We Like
  • Hydrating

  • Boosts radiance

  • Non-irritating

What We Don't Like
  • Expensive

Before you hit the sack, slather on a thin layer of this reparative night cream. It contains wrinkle-reducing retinol, radiance-boosting antioxidants, and squalane to moisturize while keeping irritation at bay.

Price at time of publish: $65

When to apply: Apply to skin at night after washing and applying serums.

Active Ingredients: Retinol, squalane, niacinamide, licorice root extract | Skin Type: All | Size: 1.7 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: Yes

Best for Crow's Feet: The Inkey List Retinol Eye Cream

The Inky List Retinol Eye Cream

Sephora

What We Like
  • Affordable

  • Non-irritating

  • Boosts radiance

What We Don't Like
  • Small amount

If you're looking to target crow's feet, your best bet is a retinol eye cream, like this supremely affordable pick from The Inkey List. It hydrates and plumps with hyaluronic acid, boosts radiance with vitamin C, and, thanks to the slow-release formula, reduces the appearance of wrinkles without the irritating effects of retinol.

Price at time of publish: $12

When to apply: Apply a dot of the product using your ring finger to the area around your eyes. For best results, use daily prior to applying makeup.

Active Ingredients: Slow-release retinol, hyaluronic acid, vitamin C | Skin Type: Balanced, mature, combination | Size: 0.5 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best for Neck: bareMinerals Ageless Phyto-Retinol Neck Cream

bareMinerals Ageless Phyto-Retinol Neck Cream

Ulta

What We Like
  • Retinol alternative

  • Non-irritating

  • Hydrating

What We Don't Like
  • Expensive

  • Contains synthetic fragrance

You don't necessarily need a designated cream for your neck, but if it helps you remember to moisturize below the chin, we're all for it. This one—which is best used at night on clean, dry skin—contains Bidens pilosa extract, a plant-derived retinol alternative that's been shown to offer similar wrinkle-reducing effects.

Price at time of publish: $52

When to apply: Apply a pea-sized amount to clean, dry skin on the neck at night.

Active Ingredients: Bidens pilosa extract, peptides, squalane, hyaluronic acid | Skin Type: All | Size: 1.7 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best Repairative: Priori DNA Intense Recovery Cream

Priori DNA Intense Recovery Cream

Amazon

What We Like
  • Prevents photoaging

  • Boosts radiance

  • Dermatologist-recommended

What We Don't Like
  • Expensive

Dermatologists love this formula. "Priori DNA Intense Recovery Cream contains DNA repair enzymes, hyaluronic acid, and vitamin C," Madfes tells Byrdie. As mentioned, DNA repair enzymes can help prevent photoaging—but this doesn't mean you can skip the sunscreen.

Price at time of publish: $113

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to makeup and don't forget sunscreen (which can also be applied prior).

Active Ingredients: DNA repair enzymes, hyaluronic acid, vitamin C, vitamin E | Skin Type: All | Size: 1.7 oz | SPF: Yes | Byrdie Clean: No | Cruelty-Free: Yes

Best Tightening: Yeouth Retinol Moisturizer

Yeouth Retinol Moisturizer

Amazon

What We Like
  • Affordable

  • Non-irritating

  • Fragrance-free

What We Don't Like
  • Small amount

For a tightening effect, reach for this wallet-friendly moisturizer. It combines two of Madfes's recommended ingredients for wrinkles (retinol and peptides), plus soothing green tea and plumping hyaluronic acid.

Price at time of publish: $15

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to makeup.

Active Ingredients: Retinol, hyaluronic acid, green tea, peptides | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: Yes

Best Firming: Dr. Dennis Gross Skincare Ferulic + Retinol Anti-Aging Moisturizer

Dr. Dennis Gross Skincare Ferulic + Retinol Anti-Aging Moisturizer

 Courtesy of Sephora

What We Like
  • Supports collagen production

  • Replenishes skin barrier

  • Dermatologist-developed

What We Don't Like
  • Expensive

Dr. Dennis Gross combines anti-aging retinol with bakuchiol and rambutan, resulting in a boost in collagen production to improve elasticity, minimize wrinkles, and deliver visibly firmer skin.

Price at time of publish: $75

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to sunscreen and makeup.

Active Ingredients: Retinol, bakuchiol, rambutan, ferulic acid | Skin Type: All | Size: 2 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best for Sensitive Skin: Plantkos Phyto A Face Lotion

Plantkos Phyto A Face Lotion

Thirteen Lune

What We Like
  • Natural formula

  • Supports collagen production

  • Calms inflammation

What We Don't Like
  • Expensive

If your skin doesn't tolerate retinol well, Plantkos Phyto A is a prime choice. It contains bakuchiol, an up-and-coming plant-derived retinol alternative that offers similar effects without any redness, stinging, or irritation.

Price at time of publish: $67

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to sunscreen and makeup.

Active Ingredients: Bakuchiol, niacinamide, vitamin C, gotu kola, ​​Schisandra sphenanthera | Skin Type: Mature, sensitive, balanced, oily, combination, acne-prone | Size: 1.7 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best for Dry Skin: BeautyStat Cosmetics Universal Pro-Bio Moisture Boost Cream

Beauty Stat Universal Pro-Bio Moisture Boost Cream
What We Like
  • Lightweight

  • Wears well under makeup

  • Replenishes skin barrier

What We Don't Like
  • Expensive

  • Small amount

Thirsty complexion? Go with BeautyStat. It calls on hyaluronic acid to draw moisture from the air, bind it to your skin, and keep it hydrated for hours on end. Not only that, but ceramides replenish the skin barrier and support its moisture mantle. The lightweight formula is also great under makeup.

Price at time of publish: $50

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to sunscreen and makeup.

Active Ingredients: Hyaluronic acid, ceramides, probiotics | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: Yes

Best for Dry Skin, Runner Up: ROSE Ingleton MD Skin Calming Booster

Rose Ingleton MD
What We Like
  • Contains hydrating ingredients

  • Promotes skin barrier health

  • Calming formula

What We Don't Like
  • Expensive

Developed by board-certified dermatologist Rose Ingelton, MD, this calming formula is ideal for those with dry skin looking to reduce the appearance of lines and wrinkles. In addition to hyaluronic acid, this multi-tasking serum includes niacinamide to promote skin barrier health, while also reducing the appearance of lines and wrinkles. It's a great retinol alternative for those with dry skin who might experience flaking or irritation from retinol products.

Price at time of publish: $70

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. Sunscreen, moisturizer and makeup can all be layered on top.

Active Ingredients: Hyaluronic acid, niacinamide | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best With Glycolic Acid: Skinergy Beauty Skin Guardian Moisturizer

Skinergy Beauty Skin Guardian Moisturizer

Skinergy Beauty

What We Like
  • Gently exfoliating

  • Calms inflammation

  • Contains organic ingredients

What We Don't Like
  • Expensive

Madfes is a fan of glycolic acid for wrinkles, as the AHA (alpha-hydroxy acid) sloughs off dead cells to reveal smoother skin underneath. This moisturizer also replenishes the skin with plant oils and calms inflammation with soothing ingredients like aloe, green tea, and reishi.

Price at time of publish: $48

When to apply: For best results, apply at night (the product could pill under makeup).

Active Ingredients: Glycolic acid, plant oils, reishi mushroom, aloe, green tea | Skin Type: All | Size: 2 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

Best Re-Texturizing: MGSkinLabs Inc Essential Antioxidant Infusion

What We Like
  • Dermatologist-developed

  • Gently exfoliating

  • Non-irritating

What We Don't Like
  • Expensive

Developed by board-certified dermatologist, Michele Green, MD, this retinol active infuses a blend of antioxidants to help deliver plump skin with diminished visible lines and wrinkles. A pure concentration of vitamins A, C, and E help cell turnover and exfoliate skin gently overnight. We love how the formula includes botanic actives like lavender, geranium, and bitter orange to help address elasticity and texture without causing irritation. Although the product is expensive, we think it's worth it, especially because the potent formula can be applied sparingly to achieve results.

Price at time of publish: $150

When to apply: Apply a pea-sized amount to clean, dry skin, at night.

Active Ingredients: Retinol, vitamins A, C, E  | Skin Type: All | Size: 1 oz | SPF: No | Byrdie Clean: Yes | Cruelty-Free: Yes

What Our Editors Say

"This formula has a velvety texture that sinks into skin immediately. I love how it helps to correct discoloration as well as soften the appearance of lines, without irritating my sensitive skin." — Jill Di Donato, Senior Commerce Editor

Best For Wrinkles and Puffiness: Neutrogena Rapid Wrinkle Repair Regenerating Cream

Neutrogena Rapid Wrinkle Repair

Ulta

What We Like
  • Dermatologist-developed and tested

  • Gently exfoliating

  • Can be used daily

What We Don't Like
  • Contains fragrance which could be irritating

This dermatologist-developed and dermatologist-tested product contains retinol—a true powerhouse—and is accessible and available over the counter at drugstores everywhere. We love how the formulation is both deeply moisturizing and also gentle, so it can even work for daily use.

Price at time of publish: $29

When to apply: Apply a pea-sized amount to clean, dry skin, either morning or night. If used in the morning, apply prior to sunscreen and makeup.

Active Ingredients: Retinol, hyaluronic acid  | Skin Type: All | Size: 1.7 oz | SPF: No | Byrdie Clean: No | Cruelty-Free: No

Final Verdict

Our best overall pick is Drunk Elephant A-Passioni, a brilliant moisturizer containing line-reducing retinol, collagen-supporting peptides, and barrier-replenishing ceramides. For a more affordable pick, consider a drugstore favorite, RoC Correxion Deep Wrinkle Night Cream, which combines retinol with resurfacing glycolic acid.

Meet the Expert

Diane Madfes, MD, PC, is a board-certified dermatologist and attending physician at Mount Sinai School of Medicine. Her New York City practice, Madfes Aesthetic Medical Center, specializes in facial rejuvenation, fillers, chemical peels, and general skin care.


Kavita Mariwalla, MD, is a double board-certified dermatologist and Mohs Surgeon with over 18 years experience in medical and cosmetic dermatology.

What To Look for in a Wrinkle Cream

Retinol

According to Kavita Mariwalla, MD, Byrdie Beauty & Wellness board member, this over-the-counter anti-aging ingredient has a proven track record of helping to stimulate collagen production to help smooth fine lines and deep wrinkles.

Alpha-Hydroxy Acids

Not only does this category of exfoliating acids help to even out skin tone and texture, one of them in particular, glycolic acid, also has some collagen-boosting effects as well.

Peptides

There's a whole new category of peptides that help with skin elasticity and firmness, both of which play a role in the formation of wrinkles and deep wrinkles, too, explains Mariwalla. Not to mention that peptides also tend to be better tolerated and elicit less sensitivity than the retinoids and acids of the world.

Vitamin C

This vitamin is a triple threat, acting as a protective antioxidant and excellent radiance-booster while also helping to stimulate collagen production for smoother, less wrinkled skin.

FAQ
  • Do wrinkle creams work?

    If you choose the right formula that contains some of the tried-and-true anti-aging ingredients we mentioned, use it diligently, and have a little bit of patience—they will work. However, it's important to remember that, no matter what type of wrinkle cream you're using, it's imperative to wear sunscreen (with broad-spectrum SPF 30 protection or higher) daily to ensure that sun damage doesn't thwart your wrinkle-fighting attempts.

  • At what age should you start using wrinkle cream?

    The age at which you start seeing wrinkles will depend largely on external and internal factors, according to Mariwalla. That being said, she says that generally speaking, your mid-20s is a good time to start an anti-aging skincare routine, including a wrinkle cream.

  • How do you apply wrinkle cream?

    For retinoid-based creams, Mariwalla recommends applying a pea-size drop of product to clean skin by dabbing it on your forehead, nose, chin, and cheeks. If the product you're using doesn't contain a retinoid, you can use about a nickel-size amount.

Why Trust Byrdie

Theresa Holland is a seasoned beauty writer and skincare devotee. She considered dozens of products for this roundup, researched peer-reviewed journals, and consulted our testing insights. Our product testers tried some of the top-rated products for weeks at a time, taking note of how well they delivered results as well as any extra product features. As a long-time retinol user, Theresa has tried a handful of items on this list, including Drunk Elephant, RoC, Neutrogena, Dr. Dennis Gross, Olay, Yeouth, CeraVe, and The Inkey List.

Updated by Jill Di Donato
Article Sources
Byrdie takes every opportunity to use high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial guidelines to learn more about how we keep our content accurate, reliable and trustworthy.
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