The 21 Best Face Serums of 2022

Best Overall: Skinceuticals C E Ferulic

4.9

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Who else recommends it? Allure, Women's Wear Daily, and InStyle all picked the Skinceuticals C E Ferulic.

What do buyers say? 4,400+ Dermstore reviewers rated this product 4 stars or above.

This is the GOAT of all serums, truly, boasting fan-favorite status among consumers, beauty editors, and dermatologists alike. Credit is due to the synergistic combo and a specially formulated ratio of three heavy-hitting antioxidants—vitamin C, ferulic acid, and vitamin E—to protect your skin from free radical damage. It’s preventative and protective, yes, but can also help improve existing signs of aging and/or sun damage, making it a solid option for pretty much anyone and everyone.

Benefits: Firms, smooths, evens skin tone, protects against free radicals | Skin Type: Dry, sensitive | Size: 1 fl. oz. | Cruelty-Free: No | Byrdie Clean: No

Best Budget: Rosen Skincare Paloma Serum

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Sure, this is affordable in its own right, but add to that the fact that it is a true multi-tasker—tackling uneven texture, tone, and preventing future breakouts—and you’ve really got yourself a steal of a deal. It touts both alpha-hydroxy and beta-hydroxy acids (in the form of glycolic acid and white willow bark, respectively), as well as grapefruit extract for a dose of vitamin C. The fruity scent is just a bonus.

Benefits: Exfoliates, unclogs pores, evens skin tone, prevents breakouts | Skin Type: Oily, acne-prone | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best Drugstore: Neutrogena Rapid Wrinkle Repair Serum

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This well-reviewed formula is inexpensive and effective, a real drugstore staple. The star of the show is a unique type of retinol, accelerated retinol SA, that helps to combat wrinkles, boosts radiance, and improve skin texture—in a matter of weeks. There are also two humectants (ingredients that attract water to the skin), hyaluronic acid and glycerin, that help keep skin plump, hydrated, and supple.

Benefits: Smooths lines, evens skin tone, boosts radiance | Skin Type: Dry, aging | Size: 1 fl. oz. | Cruelty-Free: No | Byrdie Clean: No

Best Calming: Dr. Barbara Sturm Calming Serum

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No matter whether it’s a chemical peel, a little too much sun, an international flight, or just day-to-day stress that’s making your skin freak out, this serum is the solution. (True story: Hailey Baldwin uses it whenever she travels.) Along with the brand’s hero ingredient, purslane, which hydrates and protects cell membranes from free radicals, it also has a plant-based complex of Cardiospermum, echium, and sunflower—a trio that helps quickly calm and soothe redness and irritation.

Benefits: Reduces redness, soothes irritation, hydrates, protects against free radicals | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best for Discoloration: SkinCeuticals Discoloration Defense

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Yep, that’s another SkinCeuticals product on the list. There are all kinds of radiance-boosting and spot-fading ingredients in this effective formula, namely 1% percent kojic acid, 5% niacinamide, 3% tranexamic acid, plus 5% HEPES, an ingredient that promotes exfoliation. It’s so effective that in a 12-week clinical study, participants show an average improvement of 60% in brown spots and patches. Color us impressed.

Benefits: Fades dark spots, smooths, boosts radiance, exfoliates | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: No | Byrdie Clean: Yes

Best for Large Pores: Renée Rouleau Pore + Wrinkle Perfecting Serum

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Fact: There’s nothing you can do (and no product you can use) to actually change the size of your pores. But you can do things (read: use serums) that will help make them appear less prominent, like this one, from one of Byrdie’s most beloved estheticians, Renée Rouleau. At work is a potent combo of glycolic, salicylic, and lactic acids that help to clear clogged pores, making them appear smaller. And, per the name, this blend also helps exfoliate to help fade hyperpigmentation and smooth fine lines.

Benefits: Exfoliates, clears pores, fades dark spots, smooth fine lines | Skin Type: Acne-prone | Dosage: 1 to 2 pumps | Size: 0.5 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best for Scars: Biologique Recherche Serum Placenta

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Acne scars are infamous for being tough to treat, but this healing and reparative formula can help in a big way. It contains only four ingredients—water, hydrolyzed placental protein, phenoxyethanol, ethylhexylglycerin—and works by expediting your skin’s natural healing process. To that point, we’ve found it helps fade dark circles and other pigment spots, too.

Benefits: Fades scars and dark under-eye circles | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: No | Byrdie Clean: Yes

Best Organic: Vintner's Daughter Active Botanical Serum

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Another option that has fan-favorite status, this formula is all about harnessing the power of plants. More specifically, it touts 22 active, organic, and wild-crafted botanicals that are chock-full of everything from antioxidants to vitamins to essential fatty acids. In short, it moisturizes, nourishes, and protects, a universally good pick for anyone looking to improve the overall health and quality of their skin. It’s so good and effective that the brand only makes one other product.

Benefits: Hydrates, nourishes | Skin Type: All | Dosage: 5 to 6 drops | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best Anti-Aging: SkinMedica TNS Essential Serum

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Yes, the price tag on this is pretty shocking… but so are its astounding anti-aging results. Another long-time staple of beauty editors and derms alike, it relies on growth factors and a protein and amino acid complex to regenerate skin cells, reduce inflammation, strengthen the skin, and more. (FYI, those growth factors are human-derived though, which may be off-putting to some.) Use it regularly, and you’ll absolutely see a difference.

Benefits: Smooths, firms, boosts radiance, soothes irritation | Skin Type: Aging | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No

Best With Retinol: Dr. Dennis Gross Advanced Retinol + Ferulic Texture Serum

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True story: Our mega sensitive skin could never tolerate a retinol product… until we tried this serum. We’re not quite sure how the magic formula works so well, with not even a trace of irritation, but you better believe it does. The first of its two namesake ingredients supports collagen production and minimizes the production of sebum, and the latter offers powerful antioxidant protection. It also contains bakuchiol, a plant-based ingredient that provides similar effects to retinol. The product also works super fast; we noticed an improvement in our skin’s texture, tone, and overall smoothness after a week or so.

Benefits: Targets pores, uneven texture, blemishes | Skin Type: Oily, acne-prone, aging | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No

Best Retinol Alternative: Boots Ingredients Bakuchiol Face Serum

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If you're sensitive to retinol, but after its turnover effects, consider adding bakuchiol to your routine. It’s the star of the show here, offering similar effects to retinol when it comes to collagen stimulation and improvement in texture and tone, but with no irritation.

Benefits: Targets pores, uneven texture, wrinkles | Skin Type: Aging | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No

Best Hydrating: SkinMedica HA5 Rejuvenating Hydrator

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When moisturizer alone just won’t cut it, layer this super hydrating serum underneath. The name refers to a proprietary mix of five types of hyaluronic acid; that combo works to deliver both instant and long-lasting hydration, up to eight hours worth, to be exact. The point is, your skin will instantly be more hydrated (as well as smoother, plumper, and more supple), and will stay that way all day long. The primer-like texture layers beautifully under makeup, too.

Benefits: Hydrates | Skin Type: Dry, aging | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No

Best Splurge: Augustinus Bader The Serum

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This cult-favorite serum uses the brand’s TFC8 patented technology, a combo of over 40 ingredients, and the result of over 30 years of research. In short, it works by basically helping your skin act younger, which is why this formula is ideal for tackling everything from dryness to hyperpigmentation to wrinkles to redness. 

Benefits: Hydrates, boosts radiance, smooths fine lines | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best for a Compromised Skin Barrier: BYOMA Hydrating Serum

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At the risk of greatly oversimplifying matters, the key to healthy (and beautiful) skin is a strong and healthy skin barrier. Essentially, the very outermost layer of the skin is responsible for keeping moisture in and irritants out. And there are three primary components that ensure this: ceramides, cholesterol, and fatty acids. They are the stars of this new brand’s tri-ceramide complex. All of their products contain it and docs on barrier repair, but this serum really boosts your barrier. Alongside that complex, there are also hydrating squalane and glycerin in the mix, all of which leave your skin feeling softer, smoother, and generally healthier.

Benefits: Hydrates, barrier repair | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best Exfoliating: Sunday Riley Good Genes All-in-One Lactic Acid Treatment

4.7

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Lactic acid, an alpha-hydroxy acid, is one of the more gentle acids out there. This makes it a choice pick for either sensitive skin types or for those looking for a product they can use every day sans irritation. It’s the key player in this serum, which helps to dissolve dead skin cells to improve the look of lines and wrinkles, and generally leave skin looking smooth and glowing. Fun fact: Lactic acid is also innately hydrating, so you get a little bit of that benefit, too.

Benefits: Improves texture, evens skin tone, hydrates | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No 

Best Multi-Tasking: ILIA Super Serum Skin Tint with SPF 40

4.5

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For anyone who wants to speed up their morning skincare routine and/or just wants to minimize the number of bottles in their bathroom, this one-stop shop is ideal. It really is all you need to apply to your skin in the a.m. First and foremost, you get that important dose of (mineral-based) sun protection. It also imparts a beautiful wash of color, available in 32 shades. The formula contains hydrating hyaluronic acid and plant-based squalane, plus niacinamide, to combat inflammation to even out skin tone.

Benefits: Sun protection, color, hydrates, evens skin tone | Skin Type: All | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best for Acne-Prone Skin: Dermalogica AGE Bright Clearing Serum

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Clear your complexion with this blemish bluster. It relies on salicylic acid, a beta-hydroxy acid that’s oil-soluble, meaning it can penetrate into pores to break up excess oil and unclog them. That’d be good enough for us, but the benefits don’t stop there. It combines salicylic acid with niacinamide, which is both anti-inflammatory (good for minimizing the redness and discomfort of current pimples) and boosting radiance, helping to ward off any of the discoloration that can occur after a breakout.

Benefits: Clears breakouts, boosts radiance, fades dark spots, reduces redness | Skin Type: Oily, combination, acne-prone | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: No

Best Brightening: Rose Ingleton MD Complexion Brightening Booster

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This dermatologist brand is results-driven, and touts a clean, nutrient-rich product line, infused with Dr. Ingleton's Jamaican SuperFruit Blend featuring hyaluronic acid and sugarcane, as well as citrus fruit extracts. Active ingredients also include some major complexion brighteners. A potent blend of AHAs, glycolic acid, and lactic acid target dullness and hyperpigmentation. Collagen peptides aid with discoloration and help repair skin and improving texture.

Benefits: Fades dark spots, brightens dull skin | Skin Type: Normal, dry, combination, and oily | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best for Hyperpigmentation: Eadem Milk Marvel Dark Spot Serum with Niacinamide and Vitamin C

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This fragrance-free formula is specifically calibrated for skin of color to reduce visible dark spots, hyperpigmentation, and post-acne marks with niacinamide, encapsulated vitamin C, and amber algae. The texture is silky and absorbs easily into skin, with reviewers noting it works rapidly to diminish the appearance of blemishes from cystic acne.

Benefits: Fades dark spots including hyperpigmentation, brightens dull skin, resurfaces acne blemishes | Skin Type: Normal, dry, combination, and oily | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes

Best Botanical : Vieve's Leaves Restorative Serum

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This ultra-lightweight serum melts into skin without any sticky skin feel, and visibly reduces redness and inflammation quickly. A proprietary botanical formula made from fruit stem cell technology and CBD also features broad-spectrum vitamins and antioxidants and leaves skin soft to the touch. Hyaluronic acid and organic aloe make the formula ideal for people with sensitive skin who enjoy botanical products.

Benefits: Calms inflammation, reduces redness, clears acne | Skin Type: Normal, dry, sensitive, combination, and oily | Size: 1 fl. oz. | Cruelty-Free: Yes | Byrdie Clean: Yes