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Anti-wrinkle creams come in all sorts of formulas and anti-aging ingredients can be incorporated into almost any beauty products, but the ideal formulation hits on a mix of treating the existing symptoms of aging, like dehydration and fine lines, with ingredients that help prevent future signs from becoming more visible by keeping skin bright, smooth, and even in tone. It’s worth noting that most anti-wrinkle creams work best when used with serums, eye creams, and other complementary products to make sure all your skin is covered, but if you do nothing else for your face, washing every day and applying a protective layer like an anti-wrinkle cream is a great start. Check out our top picks below.
Best Overall: AmorePacific Future Response Age Defense Creme
If you could predict the future, what would you want it to say about your skin? This superpowered anti-wrinkle cream lets you start with a practically blank slate thanks to the Future Response Complex™, a blend of AmorePacific’s signature green tea polysaccharides (they grow the green tea themselves) and pine mushroom, which are rich in antioxidants that help alleviate signs of skin irritation. Their fusion of 12 Asian botanicals further helps to reduce signs of aging, and this daily moisturizer with SPF 30 UVA/UVB protection helps ensure that your skin will look great for years to come. Made without parabens, sulfates, or phthalates, reviewers swear by this as their daily go-to.
Best Budget: Neutrogena Rapid Wrinkle Repair Moisturizer SPF 30
This retinol-infused day cream delivers anti-aging and exfoliating power to the skin while dispensing hydration through a combination of glucose complex and hyaluronic acid. It helps to smooth wrinkles fast and diminishes the look of age spots thanks to some brightening agents. As is necessary when using any retinol, this day cream has full-spectrum UVA/UVB protection at an SPF 30 to keep your skin protected and youthful-looking for the long term.
Best Drugstore Option: L’Oreal Cicacream Face Moisturizer
This is a retinol cream built for sensitive skin that might not otherwise be able to tolerate it, so rejoice – retinol for all! This fragrance-free cream uses a Chinese herb called centella Asiatica as a support for your skin’s protective barrier which weakens with age, resulting in moisture loss. That means more prominent wrinkles and greater signs of aging. But this lightweight cream is ready to tackle those skin problems right there in the drugstore aisle, helping your skin to feel healthier, softer, smoother and more supple within two weeks. Firmness, elasticity, and that inner glow will continue to improve the longer you use the cream.
Best for Body: Dr. Barbara Sturm Anti-Aging Body Cream
Your body deserves some anti-aging love too, and this anti-wrinkle lotion helps keep skin supple and smooth by combining a slew of skin-loving ingredients, including olive oil, lactic acid, vitamin C, and vitamin B5 to improve the appearance of fine lines and wrinkles. White almond and elderberry blossom firm and tighten the skin matrix, while antioxidants protect the sensitive cell membranes from free radicals. The lightweight formula absorbs quickly so it won’t slow you down as you’re dressing. If you’ve never considered what a push-up bra might be doing to your decolletage, or how sunbathing can loosen the skin on your tummy as well as your face, let this cream show you the way.
Best Face Cream: Dr. Loretta Anti-Aging Repair Moisturizer
The best anti-wrinkle face creams combine wrinkle-fighting power with rich moisturizers to help support your skin in any circumstance—including one you might not have considered. This anti-aging cream is formulated for twice-daily use, and uses antioxidants like chromabright and lipochroman to help protect your skin from pollution, chamomile, lavender and geranium essential oils to replenish moisture, and a special vitamin E derivative that helps specifically to defend against HEV light—the unique blue light emitted by computer screens and smartphones. Which means if you’re reading this sentence, you probably need to try this cream.
Best for Men: Brickell Revitalizing Anti-Aging Cream for Men
The best anti-wrinkle cream for men has to have the strength to penetrate the thicker skin on men’s faces, and that means leaning into power ingredients like DMAE, a natural muscle tightener that helps prevent wrinkles; MSM, which reduces age spots and skin pigmentation, and every moisturizer’s best friend, hyaluronic acid, the gel-like water-loving molecule that retains over 1,000 times its weight in water.
The appearance of wrinkles is always exacerbated by the dehydration of the skin as we age, so flooding your cells moisture helps reduce fine lines now and deep wrinkles later. It’s 100% natural and 81% organic, and you have the choice of unscented or scented with a blend of peppermint, eucalyptus, and lemongrass oils. Reviewers rave about the non-greasy formula and the speed at which their skin texture and appearance has improved.
Best for Older Skin: SkinCeuticals A.G.E. Interrupter Mature Skin Treatment
Just because you’ve got some wrinkles already doesn’t mean there’s nothing to be done! The best anti-wrinkle cream for older skin is designed to slows the loss of elasticity and firmness that truly changes the appearance of older skin. It prevents glycation, a molecule-bonding process whereby sugars break down the proteins in your skin that keep it looking youthful and healthy, and helps keep your collagen levels up.
Formulated with an unprecedented 30% concentration of Proxylane™, 4% blueberry extract, and 0.2% phytosphingosine, it helps restore the loss of firmness, and reduces the appearance of fine lines, wrinkles and rough skin texture by restoring water and moisture to the skin. The velvety-smooth texture is soothing and comfortable to apply to more delicate skin—you’ll feel better from the moment it goes on.
Our writers spent 5 hours researching the most popular anti-wrinkle creams on the market. Before making their final recommendations, they considered 90 different creams overall, screened options from 65 different brands and manufacturers, read over 50 user reviews (both positive and negative) and tested 2 of the creams themselves. All of this research adds up to recommendations you can trust.