The 12 Best Acne Spot Treatments to Zap Pimples Fast

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When breakouts start to push their way through the surface of the skin, many of us enter attack mode. Forget letting it run its course. It's all about acting fast and breaking out the heavy artillery. Usually, this means applying one of the best acne spot treatments we can get our hands on. 

However, know that spot treatments work best on pustules (traditional pimples filled with pus). If you have cystic acne or papules (inflamed red pimples that haven't quite reached the surface), spot treatments won't cut it. (For more info on how to treat other kinds of pimples, check out our foolproof guide.) But if you're dealing with a pesky pustule, we've got the best hard-hitting products that will shrink your skin's new resident in no time.

Keep scrolling to see the best acne spot treatments your money can buy.

Best Overall: Origins Super Spot Remover Blemish Treatment Gel

origins super spot remover

Courtesy of Origins

This gel spot treatment has everything—salicylic acid, red algae to (ironically) remove redness, and exfoliators to flush out dead skin cells and excess sebum. It's every pimple-busting weapon wrapped into one.

Breakouts clear within two to three days, with minimal scarring. Some reviewers preferred to use this at night, though the clear, unassuming gel also works during the day. As with most spot treatments, a little goes a long way. There’s even a slight tingle if you like to feel products working.

Best Classic: Kate Somerville EradiKate Acne Treatment

Kate Somerville EradiKate Acne Treatment
Courtesy of Sephora

You’ve probably seen this product’s characteristic pink formula dotted all over people’s faces on Instagram. Housed in a vaguely medical-looking glass bottle, the EradiKate Acne Treatment uses sulfur and AHAs to reduce existing pimples while preventing new ones. As the treatment shrinks pimples overnight, zinc oxide absorbs excess sebum to control oil, which helps keep the area clear. Even hormonal acne disappears faster.

Without shaking the bottle, dip a Q-Tip into the bottle, pick up the thick pink solution, and apply it to your blemish. 

Best for Whiteheads: Mario Badescu Drying Lotion

There's a reason this formula is one of the go-to spot treatments for beauty editors and celebrities alike. In short? It actually works (and fast!) to dry up whiteheads and reduce the appearance of pesky breakouts overnight. Simply dab a bit of the formula—laced with a hard-hitting combo of salicylic acid, sulfur, and zinc oxide—onto the problem spot(s) before bed, let it dry, and then hit the hay. When you wake up, rinse off the lotion and the spot should be virtually undetectable. It's that easy.

Interested in learning more about this product? Check out our Mario Badescu Drying Lotion review.

Best Budget: The Ordinary Salicylic Acid 2% Solution

The Ordinary Salicylic Acid 2% Solution
Courtesy of Sephora

As cheap as this is, it’s also effective and gentle on skin—nowhere near a clumsily formulated acid bath. The Ordinary’s solution contains acne-fighting salicylic acid as well as a milder form of witch hazel, an astringent that cuts oil and deflates pimples without choking the moisture out of your skin. Thanks to its exfoliating and soothing properties, the solution clears closed comedones, ingrown hairs, blackheads, and whiteheads while reducing redness, even balancing oily skin.

Best Drugstore: Clean & Clear Advantage Spot Treatment

Clean & Clear Advantage Spot Treatment with Witch Hazel
Courtesy of Amazon

Finally, the drugstore classic that’s available almost anywhere, if you can’t get your hands on The Ordinary’s spot treatment. The gel formula contains witch hazel and salicylic acid and comes in a tapered squeeze tube. The applicator helpfully dispenses small doses without splattering everywhere, which helps if you’re in a rush. The spot treatment dries clear and sinks in quickly as it stops developing pimples and calms ones that have already popped up.

Best with Benzoyl Peroxide: Neutrogena On-the-Spot Acne Treatment

neutrogena on the spot acne treatment

Courtesy of Walmart 

This heavy-duty spot treatment (with 2.5% benzoyl peroxide) shrinks blemishes like no one's business. However, it's quite potent, so a little goes a long way.

Check out some of our other picks of the best benzoyl peroxide products.

Best for Under Makeup: Eve Lom Dynaspot

eve lom dynaspot

Courtesy of Sephora

Formulated to suit all skin tones, this cream can be used underneath or on top of makeup to target breakouts. It's also moisturizing, so you can forget about dried-out, flaky patches. 

Peep our selection of the best acne creams for every situation.

Best Patch: Peach Slices Acne Spot Dots

acne spot dots

Courtesy of Peach & Lily

We first heard about these miraculous acne treatment dots from celebrity esthetician Angela Caglia. Her claim: That even the most stubborn of blemishes will disappear overnight. In fact, she even told us she recommends them to her highest-profile clients. In other words, they must work.

Best On-the-Go: Proactiv Emergency Blemish Relief

proactiv emergency blemish relief

Courtesy of ProActiv

This high-powered benzoyl peroxide treatment absorbs quickly into the skin for quick relief. Your blemish will be noticeably smaller by morning.

Best Daytime: Tea Tree Clear Skin Serum

In case of angry, inflamed pimples, dot this on. While labeled a serum, the fast-absorbing Tea Tree Clear Skin Serum works just as well as a spot treatment for daytime. The dropper bottle contains a potent mix of antibacterial tea tree oil, vitamin C, hyaluronic acid, salicylic acid, and even niacinamide. Together, they bring down swelling and redness, brighten, and refine skin texture while preventing future pimples from forming.

Best Overnight Treatment: Renée Rouleau Night Time Spot Lotion

renee rouleau nighttime spot treatment

Courtesy of Renee Rouleau

For those times when an angry bump rears its head practically before your eyes, Renée Rouleau's fast-acting acne spot treatment is invaluable. Specifically formulated for surface-infected blemishes, it uses a down-to-business approach with potent blemish-clearing ingredients like zinc oxide, sulfur, and camphor. 

Best for Mild Acne: Cosrx Master Pimple Patch

cosrx acne pimple master patch

Courtesy of Soko Glam

These humble hydrocolloid patches from Cosrx are ideal for sucking the gunk out of pimples and healing picked-at skin. These patches are your friend when you get too enthusiastic with extracting a pimple and accidentally create a small wound, or if you’re always touching your face. The protective covering reduces bacteria transfer while healing the skin.

The way they work is simple: Once you smooth on the patch, it slowly draws out all the oil and bacteria inside the blemish while keeping other contaminants out. They're not meant to work instantly, gradually shrinking blemishes through the least invasive means possible. The translucent patch grows opaque as it clears out the pimple, and a white dot becomes visible in the center to let you know when to remove it. 

Interested in reading more reviews? Take a look at our selection of the best acne scar treatments available online.

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